Graça Raposo

· Centre National de la Recherche Scientifique
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简介

G. Raposo received her PhD in 1989 at the Univ. Paris VII (Université de Paris) . Her work focused on the intracellular trafficking of neurotransmittor receptors exploiting imaging and in particular she gained expertise in electron microscopy. From 1990 to 1995 she was a post-doc in the Immunology Center, Marseille, where she started studying the trafficking of MHC class II molecules. Because of her expertise in EM she pursued studies in immune cells in the Dept of Cell Biology, Utrecht University, The Netherlands. While in the team of Hans Geuze she showed that B lymphocytes secrete exosomes with antigen presentation capacities leading her to pursue on understanding main cell biological principles of the generation and function of Exosomes and other ExtracellularVesicles . Since 1995 she is a team leader in the Dept of Cell Biology and Cancer. In the past 8 years she took in charge the Direction of the Training unit at Institut Curie. Her current research focus is on the biogenesis and functions of Extracellular Vesicles and lysosome related organelles, with a focus on pigment granules, with implications in disease. Distinctions : CNRS Silver Medal, Descartes Huygens Price, Royal Dutch Academy, ISEV achievement award, Raymond Castaing Price from the society for Microscopies and EMBO member since 2015.

研究方向

Extracellular vesicles in diseaseCellular transport and secretionmelanin and skin pigmentationImmunotherapy and Immune ResponsesRNA regulation and disease

数据来源: OpenAlex + ORCID + Wikidata · 数据质量: verified

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