Protein glycosylation is a fascinating posttranslational modification that modulates protein structure and function. Contrary to polypeptide parts of proteins, glycan parts are not directly encoded in our genome. Instead they are encoded in a dynamic network encompassing hundreds of genes and environmental factors. By performing large scale studies of the human glycome and genome wide associations my lab is trying to identify genes which regulate protein glycosylation in health and disease.
研究方向
Glycosylation and Glycoproteins ResearchMonoclonal and Polyclonal Antibodies ResearchGalectins and Cancer BiologyDiabetes and associated disordersCarbohydrate Chemistry and Synthesis
